Fig. 13. Hierarchical self-organization of aromatic peptide conjugates through disulphide dynamic covalent self-assembly and supramolecular polymerization: (A) molecular structure of building block 18 made of the peptide Gly–Leu–Lys–Phe–Lys tethered to the 1,3-dimercaptobenzene aromatic core; (B) schematic representation of its self-assembly at the molecular (top) and supramolecular (bottom) scales upon air oxidation, forming different macrocycles that can undergo supramolecular polymerization; (C) representation of the evolution of the constitution of the system showing the amplification of the hexamer (left) and its templated growth in the presence of seeds (right). Adapted from ref. 198 (copyright 2010, American Association for the Advancement of Science) and ref. 204.