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. 2022 Jan 26;20:22. doi: 10.1186/s12916-021-02221-z

Table 11.

Change in HbA1c values (with HbA1c denoted in mmol/mol) after acarbose titration

Acarbose dose after titration
0 50 100 150 200 300
-3(-6, -1)#m=49 -4(-7, -3)#m=221 -7(-8, -4)#m=211 -7(-11, -1)#m=37
2(0, 4)#m=52 -3(-8, 0)#m=34
4(2, 6)#m=149 3(1, 6)#m=40 -2(-6, 0)#m=72 -2(-4, 0)#m=94
4(2, 6)#m=122 0(-1, 2)#m=65 -2(-3, 0)#m=144
4(2, 7)#m=67 3(2, 6)#m=48 -1(-3, 1)#m=75
7(4, 10)#m=82 7(3, 9)#m=49 3(2, 6)#m=92

Change in HbA1c values after acarbose initiation, titration, or discontinuation. The values above the diagonal represent the instances where the medication has been initiated or up-titrated, while the values below the diagonal represent instances where the medication has been down-titrated or discontinued. The values refer to the mean difference in HbA1c (MD) and 95% confidence intervals. MD below 0 indicate a lowering in HbA1c while those above 0 indicate an increase in HbA1c. #m refers to the number of HbA1c pairs for that dose titration