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. 2022 Jan 26;20:22. doi: 10.1186/s12916-021-02221-z

Table 7.

Change in HbA1c values (with HbA1c denoted in mmol/mol) after sitagliptin titration

Sitagliptin dose after titration
0 25 50 75 100
-8(-9, -6)#m=266 -8(-9, -7)#m=411 -6(-9, -2)#m=86
8(6, 9)#m=93 -3(-4, -2)#m=225
8(6, 10)#m=156 3(0, 6)#m=56 -3(-7, 0)#m=43 -2(-4, -1)#m=439
1(-3, 6)#m=35
7(4, 9)#m=82 2(0, 3)#m=91

Change in HbA1c values after sitagliptin initiation, titration, or discontinuation. The values above the diagonal represent the instances where the medication has been initiated or up-titrated, while the values below the diagonal represent instances where the medication has been down-titrated or discontinued. The values refer to the mean difference in HbA1c (MD) and 95% confidence intervals. MD below 0 indicate a lowering in HbA1c while those above 0 indicate an increase in HbA1c. #m refers to the number of HbA1c pairs for that dose titration