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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Neuroendocrinol. 2021 Dec 13;34(1):e13074. doi: 10.1111/jne.13074

Figure 1:

Figure 1:

A simplified schematic representing some of the cascading positive feedback loops connecting inflammatory responses, vascular damage, BBB changes, and increased amyloid toxicity.