Table 1. Nearest-Neighbor Interactions between Chol and Phos in Fluid Bilayers of DPPCa.
sterol | mol % | K | ωAB (cal/mol) |
---|---|---|---|
Chol | 0 | 3.9 ± 0.3 | 8 ± 21 |
Chol | 40 | 9.2 ± 0.2 | –260 ± 7 |
Chol/DChol | 20/20 | 8.1 ± 0.7 | –220 ± 27 |
DChol | 40 | 8.3 ± 0.7 | –230 ± 28 |
Measurements were made at 45 °C in host membranes derived from DPPC and the indicated sterol(s). In each case, 2.5 mol % Phos and 2.5 mol % Chol were present.37