Table 1.

Suggested factor replacement schedule for older adult persons with hemophilia A or B without inhibitors based on WFH guidelines

Indication	Hemophilia A		Hemophilia B
	Target peak levels (%)	Duration	Target peak levels (%)	Duration
Minor surgery	50-80	Day of surgery	50-80	Day of surgery
	30-80	Days 1-5	30-80	Days 1-5
Major surgery	80-100	Day of surgery	60-80	Day of surgery
	60-80	Days 1-3	40-60	Days 1-3
	40-60	Days 4-6	30-50	Days 4-6
	30-50	Days 7-14	20-40	Days 7-14

Adapted with permission from Srivastava et al.¹⁶