Table 1. Correlations between TMPRSS2 and various gene markers of immune cells in TIMER.

Description	Gene markers	LUAD				LUSC
		None		Purity		None		Purity
		P	Cor	P	Cor	P	Cor	P	Cor
T cell	CD2	0.907	0.005	0.418	0.037	***	0.233	**	0.133
	CD3D	0.089	−0.075	0.198	−0.058	***	0.208	*	0.1
B cell (general)	CD3E	0.84	0.009	0.313	0.046	***	0.259	***	0.161
	CD19	0.285	0.047	0.0506	0.088	***	0.289	***	0.196
	CD79A	0.685	0.018	0.214	0.056	***	0.269	***	0.164
CD8+ T cell	CD8A	***	−0.154	**	−0.132	***	0.147	0.164	0.064
	CD8B	***	−0.156	**	−0.134	**	0.14	*	0.092
TAM	IL10	0.736	−0.015	0.889	0.006	***	0.277	***	0.193
	CD68	0.557	−0.026	0.992	0	***	0.251	**	0.143
Monocyte	CCL2	0.614	0.022	0.520	0.029	***	0.224	**	0.148
	CSF1R	**	0.12	***	0.152	***	0.312	***	0.206
	CD86	0.966	−0.002	0.512	0.03	***	0.3	***	0.196
M2	CD163	0.415	−0.036	0.77	−0.013	***	0.298	***	0.2
	MS4A4A	0.924	0.004	0.486	0.031	***	0.267	***	0.163
M1	VSIG4	0.825	−0.01	0.758	0.014	***	0.249	***	0.151
	PTGS2	0.265	0.049	0.352	0.042	***	0.266	***	0.223
	IRF5	*	0.097	**	0.12	0.897	−0.006	−0.024	0.598
Natural killer cell	KIR2DS4	*	−0.113	*	−0.116	**	0.129	*	0.104
	KIR3DL3	***	−0.234	***	−0.243	0.473	−0.032	0.280	−0.05
	KIR3DL2	***	−0.169	***	−0.173	**	0.126	0.0749	0.082
Neutrophils	KIR3DL1	*	−0.103	*	−0.104	**	0.141	*	0.093
	KIR2DL4	***	−0.391	***	−0.386	0.529	0.028	0.465	−0.034
	KIR2DL3	***	−0.229	***	−0.214	*	0.107	0.107	0.074
	KIR2DL1	**	−0.131	**	−0.13	**	0.124	*	0.09
	CCR7	***	0.233	***	0.295	***	0.339	***	0.26
	CEACAM8	***	0.391	***	0.394	***	0.175	***	0.172
	ITGAM	***	0.156	***	0.185	***	0.358	***	0.266
Dendritic cell	HLA-DPB1	***	0.307	***	0.358	***	0.358	***	0.266
	HLA-DRA	***	0.231	***	0.277	***	0.299	***	0.203
	HLA-DQB1	***	0.284	***	0.327	***	0.199	*	0.094
	HLA-DPA1	***	0.283	***	0.333	***	0.327	***	0.237
	CD1C	***	0.49	***	0.516	***	0.399	***	0.316
	NRP1	***	0.167	***	0.167	***	0.209	**	0.12
	ITGAX	0.0712	0.08	**	0.12	***	0.354	***	0.248