Table 1.

Sample information.

Patient Information			Sample information				General sequencing information
Patient	Gender	Age	Tooth ID	Sinus Tract	Sample ID	Sampling Site	Number of sequences	Observed OTUs	Shannon index
1	Male	40	1	Yes	A2	root canal fillings	55360	173	3.12
					A3	extraradicular biofilm	31625	241	3.50
					A4	periapical lesions	39316	241	3.48
			2	Yes	B2	root canal fillings	35541	150	3.85
					B4	extraradicular biofilm	42688	281	3.85
					B3	periapical lesions	35016	277	2.89
2	Female	29	3	No	C1	root canal fillings	45236	213	4.06
					C2	extraradicular biofilm	32855	368	3.73
					C5	periapical lesions	44039	437	4.22
					C3	periapical lesions	44751	390	4.08
			4	No	C7	root canal fillings	45498	279	3.86
					C4	extraradicular biofilm	44146	327	3.72
					C8	periapical lesions	35702	361	4.18
3	Female	45	5	No	D4	root canal fillings	73876	152	3.42
					D1	extraradicular biofilm	50636	514	4.51
					D6	periapical lesions	71284	303	3.60
4	Female	32	6	Yes	D15	extraradicular biofilm	48239	261	3.93
5	Male	47	7	No	D8	root canal fillings	34411	175	0.99
					D3	extraradicular biofilm	48212	66	1.27
					D5	periapical lesions	81702	88	0.97
6	Female	51	8	Yes	D13	root canal fillings	54876	200	2.69
					D10	periapical lesions	30569	242	3.06
7	Male	29	9	Yes	GN	root canal fillings	50432	167	1.87
					GY	extraradicular biofilm	70119	208	1.64
					RY	periapical lesions	66428	114	3.05
8	Male	32	10	No	D11	root canal fillings	39711	72	0.31
					D14	extraradicular biofilm	33234	229	2.38
					D7	periapical lesions	31693	195	0.90