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T1L/T3DM2 disseminates more efficiently than T1L following intracranial inoculation. Neonatal C57BL/6 mice were inoculated intracranially with 100 PFU of T1L or T1L/T3DM2 viruses. At days 1, 2, 4, and 8, mice were euthanized and the indicated organs were resected. Viral titers in each organ were determined by plaque assay. Error bars represent SD. *, P < 0.05; ***, P < 0.001 (determined by the Mann-Whitney test).
