Table 5.
Univariable Analysis of Variables Associated with HCC
| Variable | Hazard Ratio | 95% CI | P value | |
|---|---|---|---|---|
| Insurance Status | Uninsured | Reference | - | - |
| Insured | 0.49 | 0.31-0.78 | 0.003 | |
| Age (Years) | <60 | Reference | - | - |
| >60 | 1.07 | 0.71-1.63 | 0.731 | |
| Sex | Female | Reference | - | - |
| Male | 1.07 | 0.61-1.9 | 0.804 | |
| Ethnicity | White | Reference | - | - |
| African American | 0.78 | 0.41-1.55 | 0.865 | |
| Hispanic | 0.84 | 0.53-1.33 | 0.865 | |
| Other Ethnicity | 0.84 | 0.29-2.41 | 0.865 | |
| BMI | <25 | Reference | - | - |
| 25.0-<30 | 0.53 | 0.33-0.87 | 0.02 | |
| >30 | 0.57 | 0.34-0.97 | 0.02 | |
| Surveillance | Spontaneous | Reference | - | - |
| Surveillance | 0.66 | 0.43–0.99 | 0.047 | |
| Initial MELD | <10 | Reference | - | - |
| >10 | 1.83 | 1.2–2.79 | 0.005 | |
| Final MELD | <13 | Reference | - | - |
| >13 | 3.04 | 1.87–4.93 | <0.001 | |
| Hepatitis B | No | Reference | - | - |
| Yes | 1.00 | 0.57–1.75 | 1.00 | |
| Hepatitis C | No | Reference | - | - |
| Yes | 1.00 | 0.64–1.55 | 1.00 | |
| Milan criteria | No | Reference | - | - |
| Yes | 0.44 | 0.28–0.68 | 0.002 | |
| Transplant Referral | No | Reference | - | - |
| Yes | 0.59 | 0.38–0.93 | 0.02 | |
| Listed for Transplant | No | Reference | - | - |
| Yes | 0.09 | 0.01–0.67 | 0.003 | |
| Treatment for HCC | No | Reference | - | - |
| Yes | 0.56 | 0.37–0.85 | 0.006 | |
| Hospice Care | No | Reference | - | - |
| Yes | 2.85 | 1.85–4.38 | <0.001 |
Abbreviations: BMI, body mass index; HCC, hepatocellular carcinoma; MELD, Model for End Stage Liver Disease.