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. 2022 Jan 7;11:777627. doi: 10.3389/fcimb.2021.777627

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Copyright © 2022 Wang, Liu, Li, Li, Xu, Niu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Different taxa between the pre-treatment group (day 0) and the 180 days after-treatment group. (A) Significantly different genera of day 0 compared with the 180 days after-treatment group. Wilcoxon rank-sum test with false discovery rate correction (P < 0.05, **). (B) Taxonomic LEfSe cladogram obtained using linear discriminant analysis (LDA) effect size (LEfSe) analysis. LEfSe identified the taxa with the greatest differences in abundance between the 180 days after-treatment group and day 0. Only taxa meeting a significant LDA threshold value of >2 are shown.