Table 4.
Cox regression analysis displaying individual hazard ratio for each performance-based functional assessment and the summary score associated with each outcome and the incremental reduction in variance for each assessment in the model.
| Model | Death | ESKD | ESKD or 50% Decline in GFR | Death, ESKD, or 50% Decline in GFR | ||||||||||||
| P Value | HR (95% CI) | −2 Log Likelihood | Chi-Squared Score | P Value | HR (95% CI) | −2 Log Likelihood | Chi-Squared Score | P Value | HR (95% CI) | −2 Log Likelihood | Chi-Squared Score | P Value | HR (95% CI) | −2 Log Likelihood | Chi-Squared Score | |
| Unadjusted model | 591.40 | 420.63 | 561.16 | 1127.03 | ||||||||||||
| Adjusted model | 569.53 | 21.87 | 352.74 | 67.89 | 487.10 | 74.07 | 1063.14 | 63.89 | ||||||||
| SPPB | 0.003 | 2.43 (1.36 to 4.34) | 560.12 | 9.41 | 0.42 | 0.82 (0.40 to 1.68) | 352.09 | 0.65 | 0.34 | 1.36 (0.72 to 2.55) | 486.19 | 0.91 | 0.002 | 1.96 (1.28 to 2.99) | 1053.26 | 9.88 |
| M3SE | 0.21 | 1.49 (0.80 to 2.77) | 567.93 | 1.61 | 0.62 | 1.20 (0.59 to 2.44) | 352.49 | 0.25 | 0.92 | 1.03 (0.55 to 1.93) | 487.09 | 0.01 | 0.30 | 1.26 (0.81 to 1.95) | 1062.05 | 1.09 |
| IADL | 0.06 | 1.71 (0.97 to 2.99) | 566.18 | 3.35 | 0.17 | 0.58 (0.27 to 1.25) | 350.65 | 2.08 | 0.05 | 0.49 (0.24 to 1.00) | 482.77 | 4.33 | 0.93 | 0.98 (0.64 to 1.50) | 1063.13 | 0.01 |
| Summary score | 0.01 | 2.07 (1.16 to 3.69) | 563.34 | 6.20 | 0.56 | 0.81 (0.39 to 1.66) | 352.40 | 0.34 | 0.62 | 0.85 (0.46 to 1.59) | 486.85 | 0.26 | 0.13 | 1.39 (0.91 to 2.10) | 1060.81 | 2.33 |
Adjusted model includes baseline values for age, sex, race, body mass index, mean arterial pressure, baseline GFR, diabetes, cardiovascular disease, cancer, education, and income. HR, hazard ratio; SPPB, Short Physical Performance Battery; M3SE, Modified Mini-Mental Status Exam; IADL, Lawton Instrumental Activities of Daily Living.