Fig 5. Whole blood RNA levels vs purified CD15+ neutrophil or buffy coat levels of immune activation markers.
In a subset of COVID-19 patients, whole blood RNA was compared to RNA from purified CD15+ neutrophils (n = 16) or buffy coat (n = 22) from the same patients for 6 mRNA biomarkers using ddPCR quantitation. Each point represents a single patient quantified for ALPL (left panels) or DEFA1 (right panels) RNA in whole blood RNA vs purified CD15+ neutrophils (upper panels) or buffy coat RNA (lower panels). All RNA levels are expressed as % of ACTB in the same ddPCR measurement.
