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. 2022 Jan 26;17(1):e0261679. doi: 10.1371/journal.pone.0261679

Fig 8. Neutrophil elastase activity of purified CD15+ neutrophils from control or COVID-19 patients.

Fig 8

Panel A) Using the kinetic elastase assay shown in Fig 7, COVID-19 patient’s purified CD15+ neutrophils (n = 10) were compared to control subjects (n = 4). The left panel reports the total cell count of CD15+ neutrophils from 50 μl of blood (mean ± s.e.m.). The total elastase activity of those cells was measured in arbitrary fluorescence units per 2 hour incubation (middle panel, mean ± s.e.m.). The total elastase activity per patient was divided by the CD15+ cell count for that patient to yield the elastase activity per cell (right panel, mean ± s.e.m.). Panel B) Patients that were PCR+ for SARS-CoV2, were regrouped according to whether they received vasopressor support (n = 4) or did not receive vasopressors (n = 8), (* = p<0.05, ** = p<0.01).