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. 2022 Jan 12;12:742736. doi: 10.3389/fimmu.2021.742736

Table 1.

Clinical and demographic characteristics compared between PLWH without MetS and PLWH with MetS.

Variables PLWH without MetS PLWH with MetS pvalue
Sample (n) 100 100
Sex, Male, n (%) 90 (90.0) 90 (90.0) 1.00**
Age, mean (sd) 54.4 (9.5) 54.6 (8.5) 0.80*
Ethnicity, n (%) 0.87**
 Caucasian 88 (88.0) 86 (86.0)
 Asian 3 (3.0) 2 (2.0)
 Black 4 (4.0) 6 (6.0)
 Other/unknown 5 (5.0) 6 (6.0)
Immunodeficiency, n (%) 14 (14.0) 13 (13.0) 1.00**
Exposure to early-generation ART, n (%) 34 (34.0) 46 (46.0) 0.11**
VAT, mean (sd) 76.1 (53.6) 149.4 (71) < 0.001*
SAT, mean (sd) 111.1 (71.1) 150.6 (77.1) < 0.001*
ART_NRTI, n (%) 95 (95.0) 96 (96.0) 1.00**
ART_NNRTI, n (%) 54 (54.0) 45 (45.0) 0.26**
ART_PI, n (%) 37 (37.0) 47 (47.0) 0.20**
ART_INSTI, n (%) 16 (16.0) 21 (21.0) 0.47**
ART_other/unknown, n (%) 0 (0.0) 3 (3.0) 0.24*

*Mann-Whitney U test and **Chi-square test.

P-values in bold indicates a significant difference in the concerned variables between the two groups. Immunodeficiency was defined as the lowest CD4+ T-cell count <200 cells/µl or previous AIDS condition and exposure to early-generation ART was defined as patients medicated with thymidine analogues, didanosine and/or indinavir.