Table 1.

Levels of auto-Abs obtained by Gyros in patients with neutralizing activity against type I IFNs

	Neutralizing auto-Abs	Gyros anti-IFN-α	Gyros anti-IFN-ω
Auto-Abs neutralizing only 10 ng/ml of type I IFNs
Patient 1	Anti-IFN-α2 and anti IFN-ω	367,899**	25,908
Patient 2	Anti-IFN-α2 and anti IFN-ω	228,684**	30,122*
Patient 3	Anti-IFN-α2 and anti IFN-ω	249,683**	56,4271*
Patient 4	Anti-IFN-α2 only	0,395,918	0,540,107
Auto-Abs neutralizing only 100 pg/ml of type I IFNs
Patient 5	Anti-IFN-α2 only	65,5719*	75,3769*
Patient 6	Anti-IFN-α2 only	15,1039	69,0513*
Patient 7	Anti-IFN-ω only	46,03*	55,9145*
Patient 8	Anti-IFN-ω only	52,352*	47,1288*
Patient 9	Anti-IFN-ω only	46,5971*	72,4223*
Patient 10	Anti-IFN-ω only	86,6252*	74,1435*
Patient 11	Anti-IFN-ω only	0,426,105	0,333,437

Levels of auto-Abs against IFN-α and IFN-ω obtained by Gyros in the 11 patients with neutralizing activity are presented. Results are considered as negative if < 30, positive with intermediate titer of auto-Abs if > 30 and < 100 (*) and positive with high titer of Auto-Abs if > 100 (**)