Table 3.
Clinical characteristics of deceased patients
| Deceased patients with neutralizing auto-Abs | Deceased patients with auto-Abs without neutralizing activity or without antibodies | p values | |
|---|---|---|---|
| Demographics | |||
| n | 6 | 23 | |
| Age, mean ± standard deviation (SD), years | 74.5 ± 12.6 | 75.3 ± 11.3 | p = 0.9 |
| ≥ 65 years old | 5 (83%) | 21 (87%) | p = 1 |
| Sex (male) | 4 (67%) | 15 (65%) | p = 1 |
| Clinical features | |||
| Full engagement (patients with no limitation of care) | 1 (17%) | 6 (26%) | p = 1 |
| Diabetes | 2 (33%) | 9 (39%) | p = 1 |
| Obesity | 2 (33%) | 5 (22%) | p = 0.6 |
| Hypertension | 3 (50%) | 15 (65%) | p = 0.6 |
| History of cardiovascular disease, stroke, peripheral artery disease, heart failure | 1 (17%) | 8 (35%) | p = 0.6 |
| History of chronic obstructive pulmonary disease, asthma, emphysema, fibrosis | 0 (0%) | 4 (17%) | p = 0.5 |
| Solid organ transplantation | 1 (17%) | 0 (0%) | p = 0.2 |
| Immunosuppressant drugs and/or long-term oral corticosteroids | 2 (33%) | 2 (9%) | p = 0.2 |
| Malignancy (active) | 2 (33%) | 2 (9%) | p = 0.2 |
| Clinical outcomes | |||
| Intubed | 1 (17%) | 4 (17%) | p = 1 |
Data are presented as a number (percentage), unless otherwise noted. A Fisher test was used to analyze the effect of dichotomous variables and a Mann–Whitney test for continuous variables