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. 2022 Jan 27;42(3):459–470. doi: 10.1007/s10875-021-01203-3

Table 4.

Clinical characteristics of with auto-Abs to type I IFNs detectable but non neutralizing

Patients with intermediate titer of antibodies against type I IFNS without neutralizing activity Patients with high titer of antibodies against type I IFNS without neutralizing activity Patients with neutralizing auto-Abs against type I IFNs
n 87 11 11
Age, mean ± Standard deviation (SD), years 64.9 ± 16.2 60.5 ± 16.1 68.7 ± 14.9
 ≥ 65 years old 46 (53%) 5 (45%) 9 (82%)
Men 51 (59%) 6 (55%) 9 (82%)
Death 15 (17%) 2 (18%) 6 (55%)

Data are presented as a number (percentage), unless otherwise noted. A Fisher test was used to analyze the effect of dichotomous variables and a Mann–Whitney test for continuous variables