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. 2022 Jan 19;2022:2410530. doi: 10.1155/2022/2410530

Figure 1.

Figure 1

The acute toxicity of NEH in mice. (a) The fruiting bodies of Huaier. (b, c) No significant change in body weight of male (b) and female mice (c) was observed after intraperitoneal injection of 50, 100, 200, 400, and 800 mg/kg/day NEH. n = 4 per group. (d-e) The difference of organ weight of heart, liver, spleen, lung, and kidneys in each group. (f, g) There was no significant change in body weight of male (f) and female mice (g) in MTD test. n = 20 per group. (h) H&E staining for pathological examination in order to observe the pathological changes of organs in three groups.