Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 19;2022:2410530. doi: 10.1155/2022/2410530

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Xiao-feng Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

NEH inhibits the proliferation, migration, and invasion of GC cells. (a–c) CCK-8 assay performed to show the inhibitory effect of different concentrations (0, 12.5, 25, 50, 100, and 200 μg/ml) of NEH on the proliferation of BGC-823 (a), HGC-27 (b), and GES-1 (c) cells. (d) Western blot analysis detected the main factors in the S phase and G2/M phase: CDK2, cyclin A2, and cyclin D1. The data in (e) was presented as the mean ± SEM. ^∗P < 0.05, ^∗∗∗P < 0.001, compared with the control group. (f, g) A wound healing assay investigated the effects of NEH on the migration of BGC-823 (f) and HGC-27 (g) cells. (h-i) Transwell assay on the effects of NEH on the invasion of BGC-823 and HGC-27 cells. Representative photographs show 48 h after drug administration. ^∗∗∗P < 0.001, compared with the control group.