Figure 7.

NEH inhibits the GPR30-mediated PI3K/AKT signalling pathway. (a) Western blot analysis on the influence of NEH on GPR30 and molecules on the PI3K/AKT signalling pathway. The data in (b) were presented as the mean ± SEM. ^∗∗∗P < 0.001, compared with the control group. (c–f) Western blot analysis on the effects of NEH, G15, and G1 on the molecules of the GPR30/PI3K/AKT signalling pathway in GC cells. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, compared with the control group or NEH-treated group.