Table 1.
Different Optimization Parameters To Synthesize Curcumin-Encapsulated Liposomes Showing Sample A3 with the Most Homogeneous Distribution of Curcumin-Encapsulated Liposome with 68% Encapsulation Efficiency
| samples | solvent system | curcumin/lipid ratio | hydrating media | encapsulation efficiency (%) |
|---|---|---|---|---|
| A1 | chloroform–methanol | 1:10 | DI water | 65.3 |
| A2 | phosphate buffer | 52.7 | ||
| A3 | 1:15 | DI water | 68 | |
| A4 | phosphate buffer | 61.2 | ||
| B1 | tert-butanol–dichloromethane | 1:10 | DI water | 51 |
| B2 | phosphate buffer | 44 | ||
| B3 | 1:15 | DI water | 45.2 | |
| B4 | phosphate buffer | 48.1 |