Figure 2.

Thigh (A), quadriceps (B), and nonquadriceps (C) muscle volume determined using MRI at day 0 and after 2 and 7 days of unilateral leg immobilization following either no exercise (CON; n = 11) or 300 eccentric muscle damaging knee extensor contractions performed in both legs immediately before immobilization (DAM; n = 10). Data are presented as means with lines representing individual responses. Statistical analysis was performed with separate three-factor ANOVAs. *Within leg difference between time points (i.e. time × leg interaction), †within leg difference between groups during corresponding immobilization period (i.e. time × group interaction), and $difference between time points in immobilized leg of control group only (i.e. three-way interaction). One symbol P < 0.05, two symbols P < 0.01, three symbols P < 0.001, and four symbols P < 0.0001.