Table 2.
Association of DWI lesions with cSVD burden and degree of CAS stratified according to median MAP change.
| Units | MAP change <44 mmHg | MAP change ≥44 mmHg | ||||
|---|---|---|---|---|---|---|
| Adjusted OR (95% CI) | p‐value | Adjusted OR (95% CI) | p‐value | |||
| Small DWI lesions | ||||||
| Total cSVD burden | Per 1 score increase | Model 1 | 1.706 (1.152–2.527) | 0.008 | 1.654 (1.207–2.267) | 0.002 |
| Model 2 | 2.023 (1.231–3.323) | 0.005 | 1.515 (1.030–2.229) | 0.035 | ||
| Degree of CAS | Per 1 grade stenosis increase | Model 1 | 1.762 (0.958–3.241) | 0.069 | 0.643 (0.273–1.512) | 0.311 |
| Model 2 | 1.853 (0.868–3.958) | 0.111 | 0.447 (0.160–1.252) | 0.126 | ||
| Large DWI lesions | ||||||
| Total cSVD burden | Per 1 score increase | Model 1 | 0.788 (0.290–2.143) | 0.641 | 1.295 (0.719–2.330) | 0.389 |
| Model 2 | 0.743 (0.203–2.719) | 0.653 | 0.840 (0.384–1.840) | 0.664 | ||
| Degree of CAS | Per 1 grade stenosis increase | Model 1 | 1.584 (0.503–4.898) | 0.432 | 3.938 (1.614–9.606) | 0.003 |
| Model 2 | 1.263 (0.324–4.926) | 0.737 | 3.478 (1.127–10.736) | 0.030 | ||
Multivariate logistic regression analysis for the association of small DWI lesions with cSVD and CAS: Model 1: adjusted for age and sex. Model 2: as for model 1 plus initial hematoma volume, initial National Institutes of Health Stroke Scale, initial systolic blood pressure, ischemic stroke, diatetes mellitus, subarachnoid extension, pneumonia, hemoglobin A1c. Multivariate logistic regression analysis for the association of large DWI lesions with cSVD and CAS: Model 1: adjusted for age and sex. Model 2: as for model 1 plus initial hematoma volume, initial National Institutes of Health Stroke Scale, initial systolic blood pressure, ischemic stroke, pneumonia, fasting blood glucose. DWI, diffusion‐weighted imaging; cSVD, cerebral small vessel disease; CAS, cerebral artery stenosis; MAP, mean arterial pressures.