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. 2021 Dec 25;24:181–198. doi: 10.1016/j.omtm.2021.12.005

Table 2.

Quantification of process efficiency using enriched TCM/TSCM cells as starting material in P4–P6

Run Starting Cell No. Process Duration CD4/CD8 Ratio in HARV Expansion Ratea T Cell No. in HARV Transduction Rate of CD45+CD3+ in HARV CAR T Cell No. in HARV VCN
P4 0.12 × 108 11 days 73.2%/26.0% 166× 1.49 × 109 62.6% 0.93 × 109 3.0
P5 0.15 × 108 12 days 85.9%/9.6% 706× 2.20 × 109 41.1% 0.90 × 109 2.4
P6 0.14 × 108 12 days 85.9%/9.6% 305× 2.28 × 109 58.6% 1.34 × 109 ND

n.d., not done.

a

The expansion rate was calculated from day 2 on.