Table 1.
Demographic, clinical and anamnestic characteristics of OLP patients
| Feature (n) | Total | Female | Male | P a |
|---|---|---|---|---|
| No. (%) | No. (%) | No. (%) | ||
| Total | 268 (100) | 210 (78.4) | 58 (21.6) | – |
| Mean age (SD) | 63.9 (± 12.2) | 64.9 (± 11.7) | 60.2 (± 13.4) | 0.019 |
| Clinical features (268) | ||||
| Erosive | 112 (41.8) | 88 (41.9) | 24 (41.4) | 0.943 |
| Non-erosive | 156 (58.2) | 122 (58.1) | 34 (58.6) | |
| Extraoral involvement | 33 (12.3) | 31 (14.8) | 2 (3.4) | 0.020 |
| Treatment (268) | ||||
| Topical steroids | 42 (15.7) | 37 (17.6) | 5 (8.6) | 0.095 |
| Removable denture (265) | ||||
| Present | 63 (23.8) | 51 (24.6) | 12 (20.7) | 0.532 |
| Concomitant disease (266) | ||||
| Hypertension | 149 (56.0) | 119 (57.2) | 30 (51.7) | 0.457 |
| Hypothyroidism | 76 (28.6) | 72 (34.6) | 4 (6.9) | < 0.001 |
| Diabetes mellitus | 36 (13.5) | 29 (13.9) | 7 (12.1) | 0.712 |
| Autoimmune disease | 44 (16.5) | 40 (19.2) | 4 (6.9) | 0.025 |
| Asthma/COPD | 28 (10.5) | 26 (12.5) | 2 (3.4) | 0.047 |
| Mental disorders | 30 (11.3) | 21 (10.1) | 9 (15.5) | 0.299 |
| Allergies | 88 (33.1) | 71 (34.1) | 17 (29.3) | 0.490 |
| Medication (265) | ||||
| Antihypertensives | 140 (52.8) | 111 (53.6) | 29 (50.0) | 0.625 |
| NSAID | 41 (15.5) | 33 (15.9) | 8 (13.8) | 0.689 |
| Inhaled steroids | 14 (5.3) | 12 (5.8) | 2 (3.4) | 0.741 |
| Psychotropic drugs | 31 (11.7) | 23 (11.1) | 8 (13.8) | 0.574 |
| Proton pump inhibitors | 26 (9.8) | 22 (10.6) | 4 (6.9) | 0.398 |
| Lifestyle (265) | ||||
| Smoker | 40 (15.1) | 33 (15.9) | 7 (12.1) | 0.466 |
| Former smoker | 55 (20.8) | 44 (21.3) | 11 (19.0) | 0.704 |
Complete data for concomitant diseases were available from 266 patients and for medication, presence of removable dentures, and smoking from 265 patients
SD standard deviation; COPD chronic obstructive pulmonary disease; NSAID non-steroidal anti-inflammatory drugs
a Referring to inter-gender comparison