Table 4.
Blood and urine parameters determined at baseline (CARLA-0), first (CARLA-1) and third (CARLA-3) follow-up examination
| Parameter | CARLA-0 | CARLA-1 | CARLA-3 |
|---|---|---|---|
| Plasma and serum | |||
| Erythrocytes (RBC) | x | x | x |
| Nucleated red blood cells | – | – | x |
| Hemoglobin | x | x | x |
| Hematocrit | – | x | x |
| Leucocytes (WBC) | x | x | x |
| Lymphocytes | – | x | x |
| Neutrophilic granulocytes | – | x | x |
| Eosinophilic granulocytes | – | x | x |
| Basophilic granulocytes | – | x | x |
| Immature granulocytes | – | – | x |
| Monocytes | – | x | x |
| Platelets | – | x | x |
| Mean corpuscular volume | – | x | x |
| Mean corpuscular haemoglobin | – | x | x |
| Mean corpuscular haemoglobin concentration | – | x | x |
| Red cell distribution width | – | x | x |
| Mean platelet volume | – | x | – |
| Glucose | x | x | x |
| Glycated hemoglobin (Hba1c) | x | x | x |
| Creatinine | x | x | x |
| Triglycerides | x | x | x |
| Total cholesterol | x | x | x |
| High density lipoprotein cholesterol | x | x | x |
| Low density lipoprotein cholesterol (LDL) | x | x | x |
| Small dense LDL | – | x | – |
| Apolipoprotein A1 | – | x | x |
| Apolipoprotein B | – | x | x |
| Alanine aminotransferase | x | x | x |
| Aspartate aminotransferase | x | x | x |
| Gamma glutamyl transferase | x | x | x |
| α-Amylase | x | – | x |
| Lipase | x | – | x |
| N-terminal pro-brain-natriuretic peptide | x | x | x |
| (High-sensitivity) C reactive protein | x | x | x |
| Interleukin 1β (IL-1) | x | – | – |
| Interleukin 6 (IL-6) | x | x | x |
| Interferon γ | x | – | – |
| Tumor necrosis factor α (TNF-α) | x | – | – |
| soluble TNF-receptor 1 (sTNF-R1) | x | x | – |
| soluble TNF-receptor 2 (sTNF-R2) | x | – | – |
| Albumin | – | – | x |
| Insulin-like growth factor-1 | xa | – | x |
| Dehydroepiandrosterone sulfate | xa | – | x |
| Testosterone | xa | – | x |
| Prostate specific antigen (m) | xa | – | x |
| Ferritin (f) | xa | – | x |
| Sex hormone binding globulin | xa | – | x |
| Cystatin C | xa | – | x |
| Thyroid stimulating hormone | x | – | – |
| Free triiodothyonine | x | – | – |
| Total triiodothyonine | x | – | – |
| Free thyroxine | x | – | – |
| Total thyroxine | x | – | – |
| Antithyroglobulin antibodies | x | – | – |
| Antithyroperoxidase antibodies | x | – | – |
| Folate | x | – | – |
| Vitamin B12 | x | – | – |
| Soluble RAGE | x | xa | xa |
| AGE-specific fluorescence | x | xa | xa |
| Influenza A IgG | xa | ||
| Influenza B IgG | xa | ||
| CMV IgG/IgM | xa | ||
| Serum metabolites measured by targeted metabolomics AbsoluteIDQ p150 Kit | x | x | |
| Urine | |||
| Dip stick (bilirubin, erythrocytes, glucose, ketone, leucocytes, nitrite, pH, protein, spec. weight, urobilinogen) | x | x | x |
| Sediment (bacteria, erythrocytes, leucocytes) | – | – | x |
| Creatinine | – | – | x |
| Albumin | – | – | x |
| Uric acid | – | – | x |
aParameters determined from frozen samples as part of the third follow-up