Table 4.
Quality of direct, indirect, and network evidence for horizontal outcome
| Outcomes | Comparison | Direct evidence | Indirect evidence | Network meta-analysis | |||
|---|---|---|---|---|---|---|---|
| Odds ratio (95% CI) | Quality of evidence | Odds ratio (95% CI) | Quality of evidence | Odds ratio (95% CI) | Quality of evidence | ||
| Horizontal width change (HWch) | Auto vs Con (2 vs 1) | 1.47 (0.22, 2.71) | Moderate | 0.58 (− 0.81, 1.97) | Moderate | 0.88 (− 0.98, 2.75) | Moderate |
| CM-NonCross vs Con (3 vs 1) | 0.37 (0.14, 0.61) | Low | 1.46 (0.65, 2.27) | Moderate | − 1.08 (− 1.93, − 0.24) | Moderate | |
| Resorb:Syn vs Con (5 vs 1) | 0.08 (− 1.21, 1.39) | Low | − 0.67 (− 2.53, 1.17) | Moderate | 0.76 (− 1.50, 3.03) | Moderate | |
| CM-NonCross vs Auto (3 vs 2) | 0.01 (− 1.03, 1.05) | Low | − 0.87 (− 2.42, 0.67) | Moderate | 0.88 (− 0.98, 2.75) | Moderate | |
| Resorb:Syn vs Auto (5 vs 2) | - | - | - | - | - | - | |
| Resorb:Syn vs CM-NonCross (5 vs 3) | − 1.34 (− 2.92, 0.22) | Moderate | − 0.58 (− 2.21, 1.04) | Moderate | -0.76(-3.03,1.50) | Moderate | |
High quality (⊕ ⊕ ⊕)—we are very confident that the true effect lies close to that of the estimate of the effect. Moderate quality (⊕ ⊕ ⊕ O)—we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low quality (⊕ ⊕ OO)—our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect. Very low quality (⊕ OOO)—we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect