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. 2022 Jan 26;12(1):14. doi: 10.1038/s41408-022-00613-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Histogram of identified transcripts, assigned to fusion groups. On top of each bars the percentage of all cases. PICALM-MLLT10 (4%), SET-NUP214 (3.4%), and NUP214-ABL1 (3.4%) are the most recurrent. B Circos plot representing the fusion transcripts. C Schematic representation of MLLT10 fused polypeptide chains with relevant domains. OM-LZ and nuclear addressing signals are always conserved. D Histograms of incidence of cases by age classes and fusion groups (absolute count on y axis). ETS fusion group is constituted with only pediatric cases. ENTH epsin N-terminal homology, NES nuclear export domain, PZP pregnancy zone protein.