Table 1.
Demographics and clinical data.
| SCZ, N = 595 | BD, N = 409 | HC, N = 947 | SMD vs HCa | Subgroup comparisonsb | |
|---|---|---|---|---|---|
| Sex female, N (%) | 253 (42.5) | 240 (58.7) | 436 (46.0) | ns | HC, BD > SCZ |
| Age, mean (SD) | 31.6 (10.1) | 35.0 (12.4) | 34.0 (9.3) | 0.04 | HC, BD > SCZ |
| GAF-symptoms, mean (SD) | 45 (12) | 58 (12) | n/a | BD > SCZ | |
| GAF-function, mean (SD) | 46 (13) | 56 (13) | n/a | BD > SCZ | |
| Medication, N (%) | |||||
| Antipsychotics | 494 (83.0) | 200 (48.9) | n/a | SCZ > BD | |
| Anticonvulsants | 82 (13.8) | 147 (35.9) | n/a | BD > SCZ | |
| Lithium | 15 (2.5) | 69 (16.9) | n/a | BD > SCZ | |
| Antidepressants | 170 (28.6) | 147 (35.9) | n/a | BD > SCZ | |
| Diagnose, N (%) | |||||
| Schizophrenia | 339 (57.0) | n/a | n/a | ||
| Schizophreniform | 36 (6.1) | n/a | n/a | ||
| Schizoaffective | 85 (14.3) | n/a | n/a | ||
| Bipolar disorder 1 | 229 (56.0) | n/a | n/a | ||
| Bipolar disorder 2 | 123 (30.1) | n/a | n/a | ||
| Bipolar disorder NOS | 19 (4.6) | n/a | n/a | ||
| Major depressive disorder | 38 (9.3) | n/a | n/a | ||
| Psychosis NOS | 82 (13.8) | n/a | n/a | ||
| Brief psychotic disorder | 14 (2.4) | n/a | n/a | ||
| Delusional disorder | 39 (6.6) | n/a | n/a | ||
BD bipolar spectrum disorders, GAF general assessment of functioning scale, ns not significant, n/a not applicable, SCZ schizophrenia spectrum disorders, SMD severe mental disorders.
aP value of SMD versus HC: chi square for categorical variables, t test for continuous variables, bchi square for categorical variables, ANOVA for continuous variables.