Table 1.
ICD codes used to define comorbidities and clinical outcomes.
| Disease | ICD-9 Codes | ICD-10 Codes | Definition |
|---|---|---|---|
| Atrial fibrillation | 427.31 | I48 | Outpatient department records ≥ 3 |
| Baseline comorbidities | |||
| Peripheral vascular disease | 093.0, 437.3, 440.x, 441.x, 443.1–443.9, 47.1, 557.1, 557.9, V43.4 | I70.x, I71.x, I73.1, I73.8, I73.9, I77.1, I79.0, I79.2, K55.1, K55.8, K55.9, Z95.8, Z95.9 | Outpatient department records ≥ 3 |
| Systemic embolism | 444 | I74.01–74.09 | Outpatient department records ≥ 3 |
| Hypertension | 401, 402 | I10–I16 | Outpatient department records ≥ 3 |
| Hyperlipidemia | 272 | E78 | Outpatient department records ≥ 3 |
| Diabetes mellitus | 250 |
E10.0, E10.1, E10.9, E11.0, E11.1, E11.9 |
Outpatient department records ≥ 3 |
| Chronic liver disease | 570, 571, 572 |
B150, B160, B162, B190, K704, K72, K766, I85 |
Outpatient department records ≥ 3 |
| Ischemic stroke | 433, 434, 436 | I63, I64 | Outpatient department records ≥ 3 |
| Chronic kidney disease | 580–589 |
I12, I13, N00, N01, N02, N03, N04, N05, N07, N11, N14, N17, N18, N19, Q61 |
Outpatient department records ≥ 3 |
| Chronic lung disease |
490, 491.0, 491.1, 491.20– 491.22, 491.8, 491.9, 492.0, 492.8, 493.00–493.02 493.10–493.12, 493.20–493.22, 493.81, 493.82, 493.90–493.92, 494.0, 494.1, 495.8, 495.9, 496, 500, 502, 503, 504, 505, A323, A325 |
J44 | Outpatient department records ≥ 3 |
| Congestive heart failure | 428 |
I11.0, I13.0, I13.2, I42.0, I50, I50.1, I50.9 |
Outpatient department records ≥ 3 |
|
Transient ischemic attack |
435 | G45 | Outpatient department records ≥ 3 |
| Percutaneous coronary intervention | procedure codes of the Taiwan NHI: 33076A, 33076B, 33077A, 33077B, 33078A, 33078B | Discharge | |
| Malignancy | 140.0–208.9 | C | Outpatient department records ≥ 2 |
| Clinical outcomes | |||
|
New ischemic stroke (ischemic stroke, transient ischemic attack) |
433, 434, 436 435 |
I63, I64 G45 |
Discharge |
| Myocardial infarction | 410, 411, 412 | I21–I25 | Discharge |
|
Bleeding (intracranial hemorrhage, gastrointestinal and other critical site bleeding |
430, 431, 432, 852, 853 456.0, 456.2, 455.2, 455.5, 455.8, 530.7, 530.82, 531.0–531.6, 532.0–532.6, 533.0–533.6, 534.0–534.6, 535.0–535.6 537.83, 562.02, 562.03, 562.12 562.13 568.81, 569.3, 569.85, 578.0, 578.1, 578.9 423,0, 459.0, 568.81, 593.81, 599.7, 623.8, 626.32, 626.6, 719.1, 784.7, 784.8, 786.3 |
I60, I61, I62 K250, K260, K270, K280, K290 D62, J942, H113, H356, H431, N02, N95, R04, R31, R58 |
Discharge |