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. 2022 Jan 26;12:1417. doi: 10.1038/s41598-022-05546-8

Table 2.

Baseline characteristics of non-valvular atrial fibrillation patients who had carotid angioplasty and stent placement (CAS), according to treatment type.

Variables Before matching
Only antiplatelet agent (N = 587) Only anticoagulation agent (N = 477) A combination of antiplatelet and anticoagulation agents (N = 304) p-value
n % n % N %
Gender Female 224 38.16 232 48.64 119 39.14 0.0014
Male 363 61.84 245 51.36 185 60.86
Age, mean (SD) year 73.79 (9.29) 73.13(10.22) 71.63 (11.03) 0.008
Total cost (NT$1000) 172,839 (148,860) 188,872 (202.553) 190,859 (165,104) 0.2873
CHA2DS2-VASc score 4.261 (1.613) 4.092 (1.690) 3.783 (1.710) 0.0002
Baseline (previous history)
PVD 267 45.49 181 37.95 112 36.84 0.0117
Systemic embolism 114 19.42 113 23.69 69 22.7 0.2136
Hypertension 209 35.6 157 32.91 97 31.91 0.4710
Hyperlipidemia 365 62.18 257 53.88 156 51.32 0.0021
Diabetes mellitus 346 58.94 211 44.23 124 40.79 <0.001
Liver cirrhosis 23 3.92 16 3.35 10 3.29 0.8441
Stroke 313 53.32 270 56.60 161 52.96 0.4813
CKD 217 36.97 113 23.69 64 21.05 <0.001
COPD 309 52.64 237 49.69 136 44.74 <0.001
CHF 381 64.91 296 62.05 190 62.5 0.5911
TIA 313 53.32 272 57.02 161 52.96 0.3979
PCI 42 7.16 13 3.19 12 3.95 0.0027

NOAC, Non-vitamin K antagonist oral anticoagulant; NT$, New Taiwan dollar; SD, standard deviation; CHA2DS2-VASc, congestive heart failure, hypertension, age 75 years or older, diabetes mellitus, previous stroke/transient ischemic attack, vascular disease, age 65 to 74 years, female; PVD, peripheral vascular disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CHF, congestive heart failure; TIA, transient ischemic attack; PCI, percutaneous coronary intervention.