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. 2021 Apr 8;43(2):417–428. doi: 10.1038/s41401-021-00646-z

Fig. 3. MB increases the expression and nuclear translocation of Nrf2 in hCHs and hFLSs.

Fig. 3

Representative Western blot results for nuclear and cytoplasmic expression of Nrf2 and Keap1 in hCHs and hFLSs after TBHP treatment and treatment with or without MB. b, j Quantification of Western blot data from a (b) and i (j). Representative Western blot results for HO-1 and NQO1 in hCHs and hFLSs after TBHP treatment and treatment with or without MB. Quantification of the Western blot data from c (d) and k (l). Immunofluorescence staining for Nrf2 in hCHs and hFLSs (green: Nrf2;blue: DAPI; scale bar: 100 μm). f, n Immunohistochemical staining for Nrf2 in the affected joint cartilage and synovium of rats (scale bar: 100 μm). Quantification of the immunofluorescence staining data from e (g) and m (o). h, p Quantification of the immunohistochemical staining data from f (h) and n (p). All data represent the mean± S.D. (n = 5). *P < 0.05, **P < 0.01, and ***P < 0.001.