Fig. 1. C0818 inhibited growth and induced apoptosis in HCC cells.
a The viability of HepG2 and Sk-Hep-1 cells was analyzed by MTT assay. b The results of the colony formation assay in HepG2 and Sk-Hep-1 cells are shown. c The percentages of apoptotic HepG2 and Sk-Hep-1 cells were analyzed by flow cytometry. The data are presented as the mean ± SD (n = 3). *P < 0.05, **P < 0.01 and ***P < 0.001 versus the control.