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. 2021 Apr 13;43(2):316–329. doi: 10.1038/s41401-021-00658-9

Fig. 10. Liver-specific Bmal1 overexpression alleviates CCl4-induced liver fibrosis.

Fig. 10

a Detection of the secretion of metabolite α-KG in liver tissue by ELISA. b Protein levels of COL1α1 and αSMA in liver tissue. c Serum ALT and AST levels (n = 8). d Representative Bmal1, H&E, Masson, Sirius-red, and αSMA staining of liver tissue sections. Data are shown as the mean ± SD (n = 3) of one representative experiment; **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. vehicle mice; ###P < 0.001 vs. rAAV8-empty treated CCl4 group.