Skip to main content
. 2021 Jul 27;27(19):5299–5306. doi: 10.1158/1078-0432.CCR-21-0607

Table 1.

Association of tumor-specific MHC-II/HLA-DR expression with outcome to durvalumab and NAC.

RCB
pCR (0) I II III
n (%) n (%) n (%) n (%)
Total (n = 48) 20 (42%) 6 (13%) 16 (33%) 6 (13%)
HLA-DR ≥ 5% (n = 9) 6 (67%) 1 (11%) 1 (11%) 1 (11%)
HLA-DR < 5% (n = 39) 14 (36%) 5 (13%) 15 (38%) 5 (13%)
χ2p value (1-tailed): pCR vs. RD: P = 0.046 RCB 0/I vs. II/III: P = 0.057
Odds ratio for response (95% CI): 3.57 (0.87–14.23) 3.68 (0.81–18.81)

Abbreviation: CI, confidence interval.

Trend for significance.