Table 3.
Correlates of Entering Weight Recovery Treatment and Changes in z-BMI, z-Weight, and z-Height After Starting Methylphenidate
| Predictor | Entered Weight Recovery Treatment (WRT) | Δ z-BMI from 0 to 6 months | Δ z-BMI from 0 months to end of follow-up | Δ z-weight from 0 to 6 months | Δ z-weight from 0 months to end of follow-up | Δ z-height from 0 to 6 months | Δ z-height from 0 months to end of follow-up | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Correlation (SE) | Sig. | Correlation (SE) | Sig. | Correlation (SE) | Sig. | Correlation (SE) | Sig. | Correlation (SE) | Sig. | Correlation (SE) | Sig. | Correlation (SE) | Sig. | |
| Biometrics | ||||||||||||||
| Female | +0.04 (0.08) | −0.02 (0.09) | −0.03 (0.09) | −0.04 (0.09) | −0.01 (0.09) | +0.16 (0.08) | +0.17 (0.09) | * | ||||||
| Age in years at start of medication | −0.13 (0.08) | +0.09 (0.09) | +0.20 (0.09) | * | +0.12 (0.09) | +0.19 (0.09) | * | +0.30 (0.08) | *** | +0.16 (0.09) | ||||
| Started medication after AUXAL-projected age of slowest growth | −0.09 (0.08) | +0.04 (0.09) | +0.12 (0.09) | +0.08 (0.09) | +0.18 (0.08) | * | +0.28 (0.08) | ** | +0.14 (0.09) | |||||
| Height (z) at start of medication | −0.20 (0.08) | * | +0.19 (0.08) | * | +0.14 (0.09) | +0.24 (0.08) | ** | +0.10 (0.09) | −0.07 (0.09) | −0.13 (0.09) | ||||
| Weight (z) at start of medication | −0.44 (0.07) | *** | +0.28 (0.08) | ** | +0.07 (0.09) | +0.28 (0.08) | *** | +0.05 (0.09) | +0.08 (0.09) | +0.00 (0.09) | ||||
| BMI (z) at start of medication | −0.45 (0.07) | *** | +0.20 (0.08) | * | −0.01 (0.09) | +0.16 (0.08) | −0.01 (0.09) | +0.15 (0.09) | +0.05 (0.09) | |||||
| Midparental height in centimeters (measured or reported) | −0.09 (0.09) | +0.06 (0.09) | +0.10 (0.09) | +0.11 (0.09) | +0.11 (0.09) | −0.10 (0.09) | −0.07 (0.09) | |||||||
| Biometric deltas | ||||||||||||||
| Change in weight (z) from start of medication to +6 months | - | - | - | - | - | +0.14 (0.09) | +0.20 (0.09) | * | ||||||
| Change in weight (z) from start of medication to last available visit | - | - | - | - | - | - | +0.42 (0.07) | *** | ||||||
| Symptoms | ||||||||||||||
| Parent rating of hyperactivity/impulsivity symptoms of ADHD at study entry | −0.08 (0.09) | −0.05 (0.09) | −0.06 (0.09) | −0.04 (0.09) | −0.05 (0.09) | −0.01 (0.09) | −0.08 (0.09) | |||||||
| Parent rating of inattention symptoms of ADHD at study entry | +0.06 (0.09) | +0.06 (0.09) | −0.09 (0.09) | +0.08 (0.09) | −0.07 (0.09) | +0.02 (0.09) | +0.02 (0.09) | |||||||
| Parent rating of ODD symptoms at study entry | −0.15 (0.08) | +0.03 (0.09) | −0.09 (0.09) | +0.03 (0.09) | −0.12 (0.09) | −0.07 (0.09) | −0.12 (0.09) | |||||||
| Medication | ||||||||||||||
| Parent rating of loss of appetite at optimization was moderate/severe | +0.10 (0.09) | −0.14 (0.09) | −0.14 (0.09) | −0.20 (0.09) | * | −0.19 (0.09) | * | −0.28 (0.08) | ** | −0.16 (0.09) | ||||
| Percent of days medicated in first 6 months after starting medication | +0.37 (0.07) | *** | −0.36 (0.07) | *** | - | −0.38 (0.07) | *** | - | −0.12 (0.09) | - | ||||
| Percent of days medicated from start of medication to last available visit | +0.32 (0.08) | *** | - | −0.38 (0.08) | *** | - | −0.40 (0.07) | *** | - | −0.26 (0.08) | ** | |||
| Total MPH intake (kg) in first 6 months after starting medication | +0.33 (0.07) | *** | −0.36 (0.08) | *** | - | −0.34 (0.08) | *** | - | +0.05 (0.09) | - | ||||
| Total MPH intake (kg) from start of medication to last available visit | +0.28 (0.08) | *** | - | −0.23 (0.09) | * | - | −0.30 (0.09) | *** | - | −0.32 (0.08) | *** | |||
Note. SE = standard error, AUXAL = structural auxologic analysis model, BMI = body mass index, ADHD = Attention-Deficit/Hyperactivity Disorder, ODD = Oppositional Defiant Disorder, MPH = methylphenidate, kg = kilograms.
Correlations are Pearson correlations. “Sig.” indicates statistical significance of correlation. All models were estimated using full-information maximum likelihood and included the 141 children who ever took medication. Auxiliary variables were female, age in years at study entry, entered study after AUXAL-projected age of slowest growth, z-height at study entry, z-weight at study entry, and z-BMI at study entry.
p < .05,
p < .01,
p < .001