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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: J Pediatr. 2021 Sep 25;241:115–125.e2. doi: 10.1016/j.jpeds.2021.09.030

Table 4.

Correlates of Entering Weight Recovery Treatment and Changes in z-BMI, z-Weight, and z-Height in the First 12 Months After Starting Methylphenidate

Predictor Δ z-BMI from 0 to 12 months Δ z-weight from 0 to 12 months Δ z-height from 0 to 12 months
Correlation (SE) Sig. Correlation (SE) Sig. Correlation (SE) Sig.
Biometrics
Female −0.06 (0.09) −0.09 (0.09) +0.12 (0.09)
Age in years at start of medication +0.22 (0.09) * +0.23 (0.09) * +0.25 (0.09) **
Started medication after AUXAL-projected age of slowest growth +0.13 (0.09) +0.18 (0.09) * +0.23 (0.08) **
Height (z) at start of medication +0.06 (0.09) +0.12 (0.09) −0.06 (0.09)
Weight (z) at start of medication +0.01 (0.09) +0.04 (0.09) +0.08 (0.09)
BMI (z) at start of medication −0.04 (0.09) −0.05 (0.09) +0.12 (0.09)
Midparental height in centimeters (measured or reported) +0.06 (0.09) +0.12 (0.09) −0.04 (0.09)
Biometric deltas
Change in weight (z) from start of medication to +6 months - - +0.28 (0.08) **
Change in weight (z) from start of medication to +12 months - - +0.38 (0.08) ***
Symptoms
Parent rating of hyperactivity/impulsivity symptoms of ADHD at study entry −0.14 (0.09) −0.15 (0.09) −0.07 (0.09)
Parent rating of inattention symptoms of ADHD at study entry +0.05 (0.09) +0.04 (0.09) −0.01 (0.09)
Parent rating of ODD symptoms at study entry +0.07 (0.09) +0.03 (0.09) −0.10 (0.09)
Medication
Parent rating of loss of appetite at optimization was moderate/severe −0.02 (0.09) −0.10 (0.09) −0.21 (0.09) *
Percent of days medicated in first 12 months after starting medication −0.37 (0.08) *** −0.37 (0.08) *** −0.24 (0.09) **
Total MPH intake (kg) in first 12 months after starting medication −0.35 (0.08) *** −0.35 (0.08) *** −0.18 (0.09) *

Note. SE = standard error, AUXAL = structural auxologic analysis model, BMI = body mass index, ADHD = Attention-Deficit/Hyperactivity Disorder, ODD = Oppositional Defiant Disorder, MPH = methylphenidate, kg = kilograms.

Correlations are Pearson correlations. “Sig.” indicates statistical significance of correlation. All models were estimated using full-information maximum likelihood and included the 141 children who ever took medication. Auxiliary variables were female, age in years at study entry, entered study after AUXAL-projected age of slowest growth, z-height at study entry, z-weight at study entry, and z-BMI at study entry.

*

p < .05,

**

p < .01,

***

p < .001