Table 1.
Demographic data
| MRCLEAN (n= 127) | CRISP (n= 104) | p-value | |
|---|---|---|---|
| Age | 63 (52–73) | 68 (57–76) | 0.01 |
| Gender (f) | 63 (50%) | 52 (50%) | 1 |
| NIHSS D0 | 17 (14–21) | 18 (12–21) | 0.36 |
| Time of symptom onset to CTP (min) | 171 (110–233) | 273 (154–406) | < 0.01 |
| Time of CTP to recanalization (min) | 163 (136–217) | 142 (106–174) | < 0.01 |
| Core volume RAPID (ml) | 14.1 (0–39.9) | 7.6 (0–20.3) | 0.01 |
| mTICI score 2b – 3 * | 48 (38%) | 87 (84%) | < 0.01 |
| Final infarct volume (ml) | 51 (21.3–112.5) | 52.0 (25.7–109.0) | 0.80 |
Data are median (IQR) or n (%).
NIHSS = National Institute of Health Stroke Scale; CTP = Computed Tomography Perfusion; f = Female; mTICI = modified Thrombolysis In Cerebral Infarction;
For MR CLEAN in 48 of 75 patients (64%) randomized to the interventional arm the mTICI score was 2b-3.