Table 1:
Summary statistics of participants in the MDRD study (“Total Group”) and the subset of patients with measured GFR (mGFR) < 20 ml/min/1.73 m2 (“mGFR<20 subgroup”).
| Total Group (N=695) | mGFR<20 Subgroup (N=214) | |
|---|---|---|
| Median (IQR) or N (%) | Median (IQR) or N (%) | |
| Age, years | 52 (43, 61) | 53 (40, 60) |
| Female Sex | 267 (38.4%) | 92 (43.0%) |
| White | 596 (85.9%) | 178 (83.2%) |
| Cause of Kidney Disease | ||
| Glomerular disease | 197 (28.3%) | 64 (30.0%) |
| Polycystic kidney disease | 168 (24.2%) | 59 (27.6%) |
| Absence of one kidney | 21 (3.0%) | 7 (3.3%) |
| Hypertensive nephrosclerosis | 44 (6.3%) | 15 (7.0%) |
| Tubulointerstitial diseases | 32 (4.6%) | 9 (4.2%) |
| Urinary tract diseases | 27 (3.9%) | 10 (4.7%) |
| Other or unknown | 175 (25.2%) | 46 (21.5%) |
| Body Mass Index, kg/m2 | 26.3 (23.9, 28.9) | 25.0 (22.8, 27.2) |
| Systolic Blood Pressure, mm Hg | 129 (118, 141) | 130 (120, 143) |
| mGFR, mL/min/1.73 m2 | 28.0 (18.0, 39.3) | 14.7 (11.5, 17.4) |
| Hemoglobin (g/dL) | 12.9 (11.6, 14.1) | 11.4 (10.3, 12.7) |
| Serum albumin (g/dL) | 4.1 (3.9, 4.3) | 4.1 (3.9, 4.3) |
| Serum phosphorus (mg/dL) | 3.6 (3.2, 4.1) | 4.2 (3.6, 4.9) |
| Urine protein, g/day | 0.2 (0.1, 1.1) | 0.5 (0.2, 1.6) |
| Urine urea nitrogen, g/day | 7.0 (5.2, 10.2) | 5.5 (4.6, 7.0) |
| Never smoker | 536 (77.1%) | 165 (77.1%) |
| Type II Diabetes | 35 (5.0%) | 11 (5.1%) |
| Hypertension | 580 (83.4%) | 181 (84.6%) |
| Coronary artery disease | 68 (9.8%) | 23 (10.7%) |
| Hyperlipidemia | 163 (23.5%) | 42 (19.6%) |
| Cerebrovascular disease | 10 (1.4%) | 3 (1.4%) |
| Peripheral vascular disease | 29 (4.2%) | 5 (2.3%) |
| Peptic ulcer disease | 26 (3.7%) | 11 (5.1%) |
| Cancer | 18 (2.6%) | 7 (3.3%) |
Abbreviations: IQR: interquartile range; mGFR: measured GFR