Table 2:

Definitions of the six clinical responses considered as potential outcomes in prediction models.

Response Category	Response Criterion
Strict eGFR Response	eGFR > 90 ml/min at 1 year OR eGFR showed a 25% improvement from baseline
Relaxed eGFR Response	eGFR > 90 ml/min at 1 year OR eGFR showed no more than a 25% reduction from baseline
Strict uPCR Response	uPCR < 0.5 at 1 year
Relaxed uPCR Response	uPCR < 0.8 at 1 year
Strict Combined Response	uPCR < 0.5 AND (eGFR > 90 ml/min at 1 year OR eGFR showed a 25% improvement from baseline)
Relaxed Combined Response	uPCR < 0.8 AND (eGFR > 90 ml/min at 1 year OR eGFR showed no more than a 25% reduction from baseline)