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. Author manuscript; available in PMC: 2023 Feb 15.
Published in final edited form as: Arch Biochem Biophys. 2021 Dec 20;716:109111. doi: 10.1016/j.abb.2021.109111

Figure 2. The contents of total carotenoids detected in the liver, serum, RPE/choroids, and retina of the ApoA-I−/−/Bco2−/− mice and the Bco2−/− mice by HPLC.

Figure 2.

The level of total carotenoids in the liver of ApoA-I−/−/Bco2−/− mice was increased but reduced in serum, RPE/choroids, and retina relative to the Bco2−/− mice, suggesting HDL participates in the carotenoid transport from the liver to the eye. Twenty ApoA-I−/−/Bco2−/− mice and twenty Bco2−/− mice were used in the feeding experiments. Total carotenoids consist of lutein, zeaxanthin, and β-carotene. The carotenoids of the liver and serum were extracted from individual animals, while the ocular tissues of five animals were pooled together for carotenoid extraction. *, P<0.05. Error bars represent standard deviation.