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. Author manuscript; available in PMC: 2023 Jan 25.
Published in final edited form as: Circulation. 2021 Dec 8;145(4):259–267. doi: 10.1161/CIRCULATIONAHA.121.056705

Table 2.

Unadjusted incidence rates of atherosclerotic cardiovascular disease and all-cause mortality among those with CAC=0 at baseline (median follow up time 15.9 years)

ASCVD (per 1000-person years) All-Cause Mortality (per 1000-person years)
Cigarette smoking status
 Never 3.07 7.15
 Former 4.05 9.11
 Current 7.30 13.86
Diabetes mellitus
 No 3.46 7.79
 Yes 8.92 13.49
Hypertension
 No 2.55 5.11
 Yes 5.44 12.42
Aspirin use
 No 3.78 8.11
 Yes 5.16 11.14
Statin use
 No 3.83 8.54
 Yes 4.56 9.47
Increased waist circumference
 No 2.97 6.61
 Yes 4.14 9.09
Family history of premature ASCVD
 No 3.49 7.72
 Yes 4.54 5.98
CKD
 No 3.48 7.29
 Yes 6.75 17.06
HDL-C ≤50 mg/dL
 No 3.50 8.35
 Yes 4.31 8.85
Triglycerides ≥150 mg/dL
 No 3.65 8.42
 Yes 4.62 9.11
LDL-C ≥130 mg/dL
 No 4.02 8.96
 Yes 3.68 7.87
Lp(a) ≥50 mg/dL
 No 3.71 8.68
 Yes 4.64 8.35
hsCRP ≥2 mg/L
 No 3.33 7.58
 Yes 4.53 9.69
Calculated ASCVD risk
 <7.5% 2.09 3.67
 7.5%–<15% 6.19 11.51
 15%–<20% 5.87 16.83

Abbreviations: CHD (coronary heart disease); HDL-C (high-density lipoprotein cholesterol); LDL-C (low-density lipoprotein cholesterol); Lp(a) (lipoprotein (a)); hsCRP (high-sensitivity C-reactive protein); ASCVD (atherosclerotic cardiovascular disease)

Increased waist circumference is defined as ≥90 cm for men or ≥80 cm for women