Table 2.
Unadjusted incidence rates of atherosclerotic cardiovascular disease and all-cause mortality among those with CAC=0 at baseline (median follow up time 15.9 years)
ASCVD (per 1000-person years) | All-Cause Mortality (per 1000-person years) | |
---|---|---|
Cigarette smoking status | ||
Never | 3.07 | 7.15 |
Former | 4.05 | 9.11 |
Current | 7.30 | 13.86 |
Diabetes mellitus | ||
No | 3.46 | 7.79 |
Yes | 8.92 | 13.49 |
Hypertension | ||
No | 2.55 | 5.11 |
Yes | 5.44 | 12.42 |
Aspirin use | ||
No | 3.78 | 8.11 |
Yes | 5.16 | 11.14 |
Statin use | ||
No | 3.83 | 8.54 |
Yes | 4.56 | 9.47 |
Increased waist circumference | ||
No | 2.97 | 6.61 |
Yes | 4.14 | 9.09 |
Family history of premature ASCVD | ||
No | 3.49 | 7.72 |
Yes | 4.54 | 5.98 |
CKD | ||
No | 3.48 | 7.29 |
Yes | 6.75 | 17.06 |
HDL-C ≤50 mg/dL | ||
No | 3.50 | 8.35 |
Yes | 4.31 | 8.85 |
Triglycerides ≥150 mg/dL | ||
No | 3.65 | 8.42 |
Yes | 4.62 | 9.11 |
LDL-C ≥130 mg/dL | ||
No | 4.02 | 8.96 |
Yes | 3.68 | 7.87 |
Lp(a) ≥50 mg/dL | ||
No | 3.71 | 8.68 |
Yes | 4.64 | 8.35 |
hsCRP ≥2 mg/L | ||
No | 3.33 | 7.58 |
Yes | 4.53 | 9.69 |
Calculated ASCVD risk | ||
<7.5% | 2.09 | 3.67 |
7.5%–<15% | 6.19 | 11.51 |
15%–<20% | 5.87 | 16.83 |
Abbreviations: CHD (coronary heart disease); HDL-C (high-density lipoprotein cholesterol); LDL-C (low-density lipoprotein cholesterol); Lp(a) (lipoprotein (a)); hsCRP (high-sensitivity C-reactive protein); ASCVD (atherosclerotic cardiovascular disease)
Increased waist circumference is defined as ≥90 cm for men or ≥80 cm for women