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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: J Trauma Acute Care Surg. 2022 Feb 1;92(2):330–338. doi: 10.1097/TA.0000000000003461

Figure 6. Effect of plasma from pigs challenged by intraperitoneal necrotic tissue on porcine PMN RB.

Figure 6.

PMN sampled from a healthy pig were incubated for 25 min with either 10% plasma from control (untreated) pigs or from pigs that had undergone i.p. injection of pig-liver slurry 1 day prior. Then receptor-dependent (LTB4-induced, Panel A) and receptor-independent (PMA-induced, Panel B) respiratory burst were measured for the indicated times using the luminometer (left sided traces). Again, receptor-dependent RB is measured for a shorter time than receptor-independent RB. As in human trauma, RB by pig PMN was markedly suppressed by plasma from pigs challenged with DAMPs. AUCs were calculated (right hand graphs) and compared using one-way ANOVA / Tukey’s test (*p<0.05; **p<0.01). RLU, relative light units.