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SAR on anilines based on 10 (38017).
| |||||||
|---|---|---|---|---|---|---|---|
| Cmpd | R1 | EC50 (μM) | CC50 (μM) | Cmpd | R1 | EC50 (μM) | CC50 (μM) |
| 10 |
|
0.20 | > 50 | 17 |
|
> 10 | > 25 |
| 18 |
|
1.59 | > 50 | 19 |
|
3.84 | > 50 |
| 20 |
|
9.83 | > 100 | 21 |
|
> 10 | > 100 |
| 22 |
|
4.65 | > 100 | 23 |
|
6.30 | > 33.3 |
| 24 |
|
> 10 | > 50 | 25 |
|
> 10 | > 50 |
| 26 |
|
4.20 | > 100 | 27 |
|
4.62 | > 20 |
| 28 |
|
0.50 | > 50 | 29 |
|
0.28 | > 100 |
