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. Author manuscript; available in PMC: 2023 Feb 15.
Published in final edited form as: Neuroimage. 2021 Dec 20;247:118844. doi: 10.1016/j.neuroimage.2021.118844

Table 2.

Stimulation protocol

Study Stimulus
location
Stimulus
Intensity (°C)
Stimulus
duration
(seconds)
Trials per
subject
Other experimental manipulations
Study1 Arm 44.3, 45.3, 46.3, 47.3, 48.3, 49.3 12.5 97 Cognitive self-regulation intervention to increase or decrease pain
Study2 Arm, Foot 46, 47, 48 11 81 Combination of painful stimuli with heat-predictive visual cues for low, medium, and high pain
Study3 Arm 47, 48, 49 8 and 11 36 Heat stimuli were intermixed with physically and emotionally aversive sound stimuli
Study4 Arm 41.1 - 47.1 10 64 Combination of painful stimuli with heat-predictive auditory cues
Study5 Arm 46, 47, 48 11 48 Combination of painful stimuli with heat-predictive visual cues and with a placebo manipulation
Study6 Leg 48, 49 1.85 70 Combination of painful stimuli with heat-predictive visual cues
Study7 Arm 43.5 - 47.5 10 64 Combination of painful stimuli with intervention for perceived control (making vs. observing cue choice) and expectancy (80% vs. 50% probabilities of low pain)
Study8 Leg 48, 49, 50 1.85 96 Combination of painful stimuli with heat-predictive visual cues and unreinforced social information
Study9 Leg 46, 47, 48 12 30 Combine painful stimuli with neural feedback on suppressing NPS activity
Study10 thumbnail 4, 7 kg/cm2* 6 5 Data collected in the context of a randomized controlled trial, including a psychotherapy treatment, placebo treatment, and treatment-as-usual control group
*

Study 10 delivered pressure rather than thermal stimulation.