Table 2.

Effects of metformin and silymarin on body and testis weights and index of testis weight in different groups

Variable	Control	Diabetes	D+Met	D+Sil	p-value*
Initial body weight (gr)	255.00 $\pm$ 7.03 (2.49)	256.13 $\pm$ 6.81 (2.41)	254.88 $\pm$ 6.79 (2.40)	256.38 $\pm$ 7.96 (2.82)	1.00
Final body weight (gr)	266.38 $\pm$ 8.11 (2.87)	158.25 $\pm$ 8.71 ${}^a$ (3.08)	180.00 $\pm$ 7.33 ${}^a{}^b$ (2.59)	218.00 $\pm$ 6.16 ${}^a{}^b{}^c$ (2.18)	$\le$ 0.001
Testis weight (gr)	1.69 $\pm$ 0.04 (0.01)	0.90 $\pm$ 0.03 ${}^a$ (0.01)	1.10 $\pm$ 0.09 ${}^a{}^b$ (0.03)	1.36 $\pm$ 0.02 ${}^{a,b,c}$ (0.01)	$\le$ 0.001
Index of testis weight (%)	0.0063 (0.63 %)	0.0056 (0.56 %)	0.0061 (0.61 %)	0.0062 (0.62 %)	-
Data are presented as Mean $\pm$ SD (SE). ${}^a$ Significantly different from the control group, ${}^b$ Significantly different from the diabetic group, ${}^c$ Significantly different from the D+Met group, *One Way-ANOVA test, D: Diabetes, Met: Metformin, Sil: Silymarin