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Simplified schema of ITP pathogenesis showing the sites of action of new therapies for ITP. Stimulatory drugs are in green and inhibitory agents are shown in red. BTKIs, Bruton tyrosine kinase inhibitors; CTLA4-Ig, Cytotoxic T Lymphocyte Antigen 4 immunoglobulin G1 fusion protein; Anti-BLys, B lymphocyte stimulator; BAFF, B cell Activating Factor.
