Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 13;8:811187. doi: 10.3389/fvets.2021.811187

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Duan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The mechanism of PDCoV interfered with IFN response. dsRNA, double-strand RNA; RIG-I, retinoic acid-inducible gene I; MDA5, melanoma differentiation-associated protein 5; PACT, protein activator of protein kinase R; TRIM25, tripartite motif containing 25; MAVS, mitochondrial antiviral signaling protein; TRAF3, tumor necrosis factor receptor associated factor; TBK1, TANK-binding kinase 1; IKK, IκB kinase; IRF, interferon regulatory factor; NEMO, NF-κB essential modulator; IκB, NF-κB inhibitor; NF-κB, nuclear factor-kappaB; IFNAR, IFN-α/β receptor; TYK2, tyrosine kinase 2; JAK1, Janus kinase 1; STAT, signal transducer and activator of transcription; ISG, interferon-stimulated gene.