TABLE 7.

Simple effects of prolonged treatment time on PI3K-AKT1 signaling pathway ANOVA.

Time factor	PI3K p85		PTEN		PDK1		AKT		NF-κB
	F	P	F	P	F	P	F	P	F	P
Day 1–Day 3	39.92	<0.0001	25.21	<0.0001	0.61	= 0.4384	34.92	<0.0001	1,205.14	<0.0001
Day 3–Day 7	213.06	<0.0001	0.08	= 0.7727	40.29	<0.0001	0	1	16.81	= 0.0002
Day 7–Day 14	171.97	<0.0001	181.13	<0.0001	512.09	<0.0001	78.27	<0.0001	15.23	= 0.0003